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Small-molecule agonists and antagonists of the opioid receptor-like receptor (ORL1, NOP): Ligand-based analysis of structural factors influencing intrinsic activity at NOP

The recently discovered fourth member of the opioid receptor family, the nociceptin receptor (NOP) and its endogenous ligand, the heptadecaptide nociceptin, are involved in several central nervous system pathways, such as nociception, reward, tolerance, and feeding. The discovery of small-molecule l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zaveri, Nurulain, Jiang, Faming, Olsen, Cris, Polgar, Willma, Toll, Lawrence
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer-Verlag 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750971/
https://ncbi.nlm.nih.gov/pubmed/16353914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj070234
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