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Use of anatomical and kinetic models in the evaluation of human food additive safety

Toxicological testing in animals is relied upon as a surrogate for clinical testing of most food additives. Both animal and human clinical test results are generally available for direct additives when high levels of exposure are expected. Limited animal studies or in vitro test results may be the o...

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Detalles Bibliográficos
Autor Principal: Roth, William L.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2005
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750968/
https://ncbi.nlm.nih.gov/pubmed/16353912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj070231
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