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Use of anatomical and kinetic models in the evaluation of human food additive safety

Toxicological testing in animals is relied upon as a surrogate for clinical testing of most food additives. Both animal and human clinical test results are generally available for direct additives when high levels of exposure are expected. Limited animal studies or in vitro test results may be the o...

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Detalhes bibliográficos
Autor principal: Roth, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750968/
https://ncbi.nlm.nih.gov/pubmed/16353912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj070231
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