Thymic involution and immune reconstitution

Chronic thymus involution associated with aging results in less efficient T-cell development and decreased emigration of naïve T cells to the periphery. Thymic decline in the aged is linked to increased morbidity and mortality in a wide range of clinical settings. Negative consequences of these effe...

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Bibliografiske detaljer
Main Authors: Lynch, Heather E., Goldberg, Gabrielle L., Chidgey, Ann, Van den Brink, Marcel R.M., Boyd, Richard, Sempowski, Gregory D.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750859/
https://ncbi.nlm.nih.gov/pubmed/19540807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2009.04.003
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