LX211 (Voclosporin) Suppresses Experimental Uveitis and Inhibits Human T Cells

PURPOSE: To test the therapeutic effectiveness of voclosporin against experimental autoimmune uveoretinitis (EAU) in rats and to evaluate its effect on human T cells. METHODS: EAU was induced by immunization with a uveitogenic protein. Voclosporin administration, by subcutaneous injection, began on...

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Main Authors: Cunningham, Matthew A., Austin, Bobbie Ann, Li, Zhuqing, Liu, Baoying, Yeh, Steven, Chan, Chi-Chao, Anglade, Eddy, Velagaleti, Poonam, Nussenblatt, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750843/
https://ncbi.nlm.nih.gov/pubmed/18708627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-1891
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