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Oral voclosporin: novel calcineurin inhibitor for treatment of noninfectious uveitis

Voclosporin, a novel immunomodulatory drug inhibiting the calcineurin enzyme, was developed to prevent organ graft rejection and to treat autoimmune diseases. The chemical structure of voclosporin is similar to that of cyclosporine A, with a difference in one amino acid, leading to superior calcineu...

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Detalhes bibliográficos
Main Authors: Roesel, Martin, Tappeiner, Christoph, Heiligenhaus, Arnd, Heinz, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180504/
https://ncbi.nlm.nih.gov/pubmed/21966207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S11125
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