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PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

BRCA1 and BRCA2 are often mutated in familial breast and ovarian cancer. Both tumor suppressors play key roles in the DNA-damage response [1, 2]. However, it remains unclear whether these two tumor suppressor function together in the same DNA-damage response pathway. Here, we show that BRCA1 associa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Feng, Ma, Jianglin, Wu, Jiaxue, Ye, Lin, Cai, Hong, Xia, Bing, Yu, Xiaochun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750839/
https://ncbi.nlm.nih.gov/pubmed/19268590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.02.018
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