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Enhancement of iontophoretic transport of diphenhydramine hydrochloride thermosensitive gel by optimization of pH, polymer concentration, electrode design, and pulse rate

The purpose of the present study was to explore the passive and electrically assisted transdermal transport of diphenhydramine hydrochloride (DPH) by iontophoresis. For better bioavailability, better patient compliance, and enhanced delivery of DPH, an iontophoretic drug delivery system of a thermos...

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Autores principales: Kotwal, Vikram, Bhise, Kiran, Thube, Rahul
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750706/
https://ncbi.nlm.nih.gov/pubmed/18181541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0804120
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