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Enhancement of iontophoretic transport of diphenhydramine hydrochloride thermosensitive gel by optimization of pH, polymer concentration, electrode design, and pulse rate

The purpose of the present study was to explore the passive and electrically assisted transdermal transport of diphenhydramine hydrochloride (DPH) by iontophoresis. For better bioavailability, better patient compliance, and enhanced delivery of DPH, an iontophoretic drug delivery system of a thermos...

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Detalhes bibliográficos
Main Authors: Kotwal, Vikram, Bhise, Kiran, Thube, Rahul
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750706/
https://ncbi.nlm.nih.gov/pubmed/18181541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0804120
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