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Nanoprecipitation versus emulsion-based techniques for the encapsulation of proteins into biodegradable nanoparticles and process-related stability issues

The goal of this study was to investigate the entrapment of 3 different model proteins (tetanus toxoid, lysozyme, and insulin) into poly(D,L-lactic acid) and poly(D,L-lactic-co-glycolic acid) nanoparticles and to address process-related stability issues. For that purpose, a modified nanoprecipitatio...

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Detalles Bibliográficos
Main Authors: Bilati, Ugo, Allémann, Eric, Doelker, Eric
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750607/
https://ncbi.nlm.nih.gov/pubmed/16408861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt060474
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