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Comparative determination of polymorphs of indomethacin in powders and tablets by chemometrical near-infrared spectroscopy and X-ray powder diffractometry

The purpose of this research was to develop a rapid chemometrical method based on near-infrared (NIR) spectroscopy to determine indomethacin (IMC) polymorphic content in mixed pharmaceutical powder and tablets. Mixed powder samples with known polymorphic contents of forms α and γ were obtained from...

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Detalhes bibliográficos
Main Authors: Otsuka, Makoto, Kato, Fumie, Matsuda, Yoshihisa, Ozaki, Yukihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750597/
https://ncbi.nlm.nih.gov/pubmed/12916901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt040219
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