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Quantitative Determination of Hydrate Content of Theophylline Powder by Chemometric X-ray Powder Diffraction Analysis

The purpose of this study was to establish a calibration model to predict the hydrate content in powder materials consisting of anhydrate (theophylline anhydrate (THA)) and theophylline monohydrate (THM) by using various kinds of X-ray powder diffraction (XRPD) analytical methods. XRPD profiles were...

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Detalhes bibliográficos
Main Authors: Otsuka, Makoto, Kinoshita, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850470/
https://ncbi.nlm.nih.gov/pubmed/20127211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9357-4
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