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Porous bone morphogenetic protein-2 microspheres: Polymer binding and in vitro release

This research compared the binding and release of recombinant human bone morphogenetic protein 2 (rhBMP-2) with a series of hydrophobic and hydrophilic poly-lactide-co-glycolide (PLGA) copolymers. Porous microspheres were produced via a double emulsion process. Binding and incorporation of protein w...

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Detalhes bibliográficos
Main Authors: Schrier, Jay A., DeLuca, Patrick P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750582/
https://ncbi.nlm.nih.gov/pubmed/14727876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt020317
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