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Effect of a freeze-dried CMC/PLGA microsphere matrix of rhBMP-2 on bone healing

The hypothesis of this research was that implants of poly(lactide-co-glycolide) (PLGA) microspheres loaded with bone morphogenetic protein-2 (rhBMP-2) and distributed in a freeze-dried carboxymethylcellulose (CMC) matrix would produce more new bone than would matrix implants of non-protein-loaded mi...

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Détails bibliographiques
Auteurs principaux: Schrier, Jay A., Fink, Betsy F., Rodgers, Janet B., Vasconez, Henry C., DeLuca, Patrick P.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750583/
https://ncbi.nlm.nih.gov/pubmed/14727877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt020318
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