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Pellet manufacturing by extrusion-spheronization using process analytical technology

The aim of this study was to investigate the phase transitions occurring in nitrofurantoin and theophylline formulations during pelletization by extrusion-spheronization. An at-line process analytical technology (PAT) approach was used to increase the understanding of the solid-state behavior of the...

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Библиографические подробности
Главные авторы: Sandler, Niklas, Rantanen, Jukka, Heinämäki, Jyrki, Römer, Meike, Marola, Martti, Yliruusi, Jouko
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750529/
https://ncbi.nlm.nih.gov/pubmed/16353975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt060226
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