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Method to recover a lipophilic drug from hydroxypropyl methylcellulose matrix tablets

A reverse-phase high-performance liquid chromatographic (HPLC) method for recovery of the lipophilic drug, alprazolam, from matrix tablets containing the hydrophilic polymer hydroxypropyl methylcellulose (HPMC) was developed. Lipophilic drugs, such as alprazolam, are difficult to completely extract...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Williams, Robert O., Sykora, Matthew A., Mahaguna, Vorapann
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750474/
https://ncbi.nlm.nih.gov/pubmed/14727883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt020208
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