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Degradation kinetics and mechanism of RH1, a new anti-tumor agent: A technical note
The degradation of RH1 in aqueous solution is found to be both acid and base catalyzed. The maximum stability is obtained in neutral pH but still degrades by 10% (t(90)) after just 1 week. The stability profile at pH 5 was done, and 4 major degradation products were observed in acid solutions. LC-MS...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer-Verlag
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750426/ https://ncbi.nlm.nih.gov/pubmed/18181534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0801016 |
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