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Effect of pH-sodium lauryl sulfate combination on solubilization of PG-300995 (an Anti-HIV agent): A technical note
Solubilization of PG-300995 has been achieved using SLS at low pH. However, at a pH where both the solute and surfactant are ionized, desolubilization can occur owing to the formation of an insoluble estolate salt. This salt can be solubilized by higher concentrations of SLS.
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer-Verlag
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750268/ https://ncbi.nlm.nih.gov/pubmed/15760078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt050345 |
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