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Preparation, in vitro release, in vivo absorption and biocompatibility studies of insulin-loaded microspheres in rabbits
The purpose of this study was to develop a single-dose insulin delivery system based on poly (lactide-co-glycolide) (PLGA) microspheres to provide basal insulin level for a prolonged period. Insulin-loaded PLGA microspheres were prepared by water-in-oil-in-water double emulsion (batch A) and solid-i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750395/ https://ncbi.nlm.nih.gov/pubmed/16354009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt060361 |
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