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Formation of acylated growth hormone-releasing peptide-6 by poly(lactide-co-glycolide) and its biological activity

The purpose of this study was to investigate the formation of acylated impurity resulting from a chemical reaction between the growth hormone-releasing peptide-6 (GHRP-6) and poly(lactide-co-glycolide) (PLGA) and the effect of peptide acylation on the in vivo biological activity of GHRP-6. The pepti...

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Detalhes bibliográficos
Main Authors: Na, Dong Hee, Lee, Jeong Eun, Jang, Sun Woo, Lee, Kang Choon
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750358/
https://ncbi.nlm.nih.gov/pubmed/18181526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0802043
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