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Formation of acylated growth hormone-releasing peptide-6 by poly(lactide-co-glycolide) and its biological activity
The purpose of this study was to investigate the formation of acylated impurity resulting from a chemical reaction between the growth hormone-releasing peptide-6 (GHRP-6) and poly(lactide-co-glycolide) (PLGA) and the effect of peptide acylation on the in vivo biological activity of GHRP-6. The pepti...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer-Verlag
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750358/ https://ncbi.nlm.nih.gov/pubmed/18181526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0802043 |
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