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The effect of drug concentration and curing time on processing and properties of calcium alginate beads containing metronidazole by response surface methodology

The purpose of present research work was to prepare calcium alginate beads containing water-soluble drug metronidazole using 3(2) factorial design, with drug concentration and curing time as variables. Curing time was kept as low as possible to improve entrapment with increasing drug concentration....

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Main Authors: Patel, Yagnesh L., Sher, Praveen, Pawar, Atmaram P.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750323/
https://ncbi.nlm.nih.gov/pubmed/16584155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070486
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