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The effect of drug concentration and curing time on processing and properties of calcium alginate beads containing metronidazole by response surface methodology
The purpose of present research work was to prepare calcium alginate beads containing water-soluble drug metronidazole using 3(2) factorial design, with drug concentration and curing time as variables. Curing time was kept as low as possible to improve entrapment with increasing drug concentration....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750323/ https://ncbi.nlm.nih.gov/pubmed/16584155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070486 |
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