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Optimization of bilayer floating tablet containing metoprolol tartrate as a model drug for gastric retention

The purpose of the present study was to develop an optimized gastric floating drug delivery system (GFDDS) containing metoprolol tartrate (MT) as a model drug by the optimization technique. A 2(3) factorial design was employed in formulating the GFDDS with total polymer content-to-drug ratio (X(1)),...

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Detalhes bibliográficos
Main Authors: Narendra, C., Srinath, M. S., Babu, Ganesh
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750284/
https://ncbi.nlm.nih.gov/pubmed/16584154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070234
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