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Optimization of bilayer floating tablet containing metoprolol tartrate as a model drug for gastric retention
The purpose of the present study was to develop an optimized gastric floating drug delivery system (GFDDS) containing metoprolol tartrate (MT) as a model drug by the optimization technique. A 2(3) factorial design was employed in formulating the GFDDS with total polymer content-to-drug ratio (X(1)),...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer-Verlag
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750284/ https://ncbi.nlm.nih.gov/pubmed/16584154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070234 |
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