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Statistical optimization of gastric floating system for oral controlled delivery of calcium
The development of an optimized gastric floating drug delivery system is described. Statistical experimental design and data analysis using response surface methodology is also illustrated. A central, composite Box-Wilson design for the controlled release of calcium was used with 3 formulation varia...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750255/ https://ncbi.nlm.nih.gov/pubmed/14727887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt020101 |
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