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Statistical optimization of gastric floating system for oral controlled delivery of calcium

The development of an optimized gastric floating drug delivery system is described. Statistical experimental design and data analysis using response surface methodology is also illustrated. A central, composite Box-Wilson design for the controlled release of calcium was used with 3 formulation varia...

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Bibliografiske detaljer
Main Authors: Li, Shoufeng, Lin, Senshang, Chien, Yie W., Daggy, Bruce P., Mirchandani, Haresh L.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750255/
https://ncbi.nlm.nih.gov/pubmed/14727887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt020101
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