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Evaluation of porous carrier-based floating orlistat microspheres for gastric delivery

The purpose of this research was to prepare floating microspheres consisting of (1) calcium silicate as porous carrier; (2) orlistat, an oral anti-obesity agent; and (3) Eudragit S as polymer, by solvent evaporation method and to evaluate their gastro-retentive and controlled-release properties. The...

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Detalhes bibliográficos
Main Authors: Jain, Sunil K., Agrawal, Govind P., Jain, Narendra K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750327/
https://ncbi.nlm.nih.gov/pubmed/17233542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070490
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