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Response surface methodology for the optimization of ubiquinone self-nanoemulsified drug delivery system
The aim of the present study was to prepare and evaluate an optimized, self-nanoemulsified drug delivery system of ubiquinone. A 3-factor, 3-level Box-Behnken design was used for the optimization procedure with the amounts of Polyoxyl 35 castor oil (X(1)), medium-chain mono- and diglyceride (X(2)),...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750250/ https://ncbi.nlm.nih.gov/pubmed/12916956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt030103 |
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