HAT–HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress

Histone acetylation and deacetylation are important for gene regulation. The histone acetyltransferase, Gcn5, is an activator of transcriptional initiation that is recruited to gene promoters. Here, we map genome-wide Gcn5 occupancy and histone H3K14ac at high resolution. Gcn5 is predominantly local...

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Bibliografiske detaljer
Main Authors: Johnsson, Anna, Durand-Dubief, Mickaël, Xue-Franzén, Yongtao, Rönnerblad, Michelle, Ekwall, Karl, Wright, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Scientific Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750064/
https://ncbi.nlm.nih.gov/pubmed/19633696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.127
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