HAT–HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress

Histone acetylation and deacetylation are important for gene regulation. The histone acetyltransferase, Gcn5, is an activator of transcriptional initiation that is recruited to gene promoters. Here, we map genome-wide Gcn5 occupancy and histone H3K14ac at high resolution. Gcn5 is predominantly local...

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Bibliographische Detailangaben
Hauptverfasser: Johnsson, Anna, Durand-Dubief, Mickaël, Xue-Franzén, Yongtao, Rönnerblad, Michelle, Ekwall, Karl, Wright, Anthony
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Scientific Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750064/
https://ncbi.nlm.nih.gov/pubmed/19633696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.127
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