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PPARγ AF-2 Domain Functions as a Component of a Ubiquitin-dependent Degradation Signal
The nuclear hormone receptor peroxisome proliferator-activated receptor gamma (PPARγ) functions as the “master switch” in adipocyte development and is important in regulating glucose metabolism. PPARγ is rapidly degraded in adipocytes by the ubiquitin proteasome pathway under basal and ligand-activa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750041/ https://ncbi.nlm.nih.gov/pubmed/19148122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2008.616 |
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