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Method for the Simultaneous Quantitation of Apolipoprotein E Isoforms using Tandem Mass Spectrometry

Using Apolipoprotein E (ApoE) as a model protein, we developed a protein isoform analysis method utilizing Stable Isotope Labeling Tandem Mass Spectrometry (SILT MS). ApoE isoforms are quantitated using the intensities of the b and y ions of the (13)C-labeled tryptic isoform-specific peptides versus...

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Autors principals: Wildsmith, Kristin R., Han, Bomie, Bateman, Randall J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749897/
https://ncbi.nlm.nih.gov/pubmed/19653990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.07.049
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