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Modeling Neuronal Nicotinic and GABA Receptors: Important Interface Salt-Links and Protein Dynamics

Protein motions in the Cys-loop ligand-gated ion receptors that govern the gating mechanism are still not well understood. The details as to how motions in the ligand-binding domain are translated to the transmembrane domain and how subunit rotations are linked to bring about the cooperative movemen...

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Detalhes bibliográficos
Main Authors: Law, Richard J., Lightstone, Felice C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749782/
https://ncbi.nlm.nih.gov/pubmed/19751663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.06.044
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