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Modeling Neuronal Nicotinic and GABA Receptors: Important Interface Salt-Links and Protein Dynamics
Protein motions in the Cys-loop ligand-gated ion receptors that govern the gating mechanism are still not well understood. The details as to how motions in the ligand-binding domain are translated to the transmembrane domain and how subunit rotations are linked to bring about the cooperative movemen...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749782/ https://ncbi.nlm.nih.gov/pubmed/19751663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.06.044 |
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