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The Origin of Allosteric Functional Modulation: Multiple Pre-existing Pathways
While allostery draws increasing attention, not much is known about allosteric mechanisms. Here we argue that in all proteins, allosteric signals transmit through multiple, pre-existing pathways; which pathways dominate depend on protein topologies, specific binding events, covalent modifications an...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749652/ https://ncbi.nlm.nih.gov/pubmed/19679084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.06.008 |
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