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The Origin of Allosteric Functional Modulation: Multiple Pre-existing Pathways

While allostery draws increasing attention, not much is known about allosteric mechanisms. Here we argue that in all proteins, allosteric signals transmit through multiple, pre-existing pathways; which pathways dominate depend on protein topologies, specific binding events, covalent modifications an...

詳細記述

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書誌詳細
主要な著者: del Sol, Antonio, Tsai, Chung-Jung, Ma, Buyong, Nussinov, Ruth
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749652/
https://ncbi.nlm.nih.gov/pubmed/19679084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.06.008
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