Identification of a Copper-Binding Metallothionein in Pathogenic Mycobacteria

A screen of a genomic library from Mycobacterium tuberculosis (Mtb) identified a small, unannotated open reading frame (MT0196) that encodes a 4.9-kDa, cysteine-rich protein. Despite extensive nucleotide divergence, the amino acid sequence is highly conserved among mycobacteria that are pathogenic i...

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Bibliographic Details
Main Authors: Gold, Ben, Deng, Haiteng, Bryk, Ruslana, Vargas, Diana, Eliezer, David, Roberts, Julia, Jiang, Xiuju, Nathan, Carl
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749609/
https://ncbi.nlm.nih.gov/pubmed/18724363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.109
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