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Stoichiometry and cluster specificity of copper binding to metallothionein: homogeneous metal clusters.

Experiments were done to define the stoichiometry of binding of Cu(I) to metallothionein (MT) and to determine its sites of binding in mixed-metal species. Spectrophotometric titrations of rabbit liver Cd7-MT 2, apoMT, and Cd4-alpha-domain with Cu(I) revealed endpoints of 3-4, 4 and 8, and 4 and 6-7...

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Detalles Bibliográficos
Main Authors: Chen, P, Munoz, A, Nettesheim, D, Shaw, C F, Petering, D H
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217501/
https://ncbi.nlm.nih.gov/pubmed/8713064
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