Interindividual Variability in Pharmacokinetics of Generic Nucleoside Reverse Transcriptase Inhibitors in TB/HIV Co-infected Ghanaian Patients: UGT2B7*1C is Associated with Faster Zidovudine Clearance and Glucuronidation

There are limited data on the pharmacokinetics of generic nucleoside reverse transcriptase inhibitors (NRTIs) in native African populations, where they are commonly used. We characterized the pharmacokinetics of lamivudine (n=27), zidovudine (n=16) and stavudine (n=11) in HIV/TB co-infected Ghanaian...

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Main Authors: Kwara, Awewura, Lartey, Margaret, Boamah, Isaac, Rezk, Naser L., Oliver-Commey, Joseph, Kenu, Ernest, Kashuba, Angela D.M., Court, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749505/
https://ncbi.nlm.nih.gov/pubmed/19628728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270009338482
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