Interindividual Variability in Pharmacokinetics of Generic Nucleoside Reverse Transcriptase Inhibitors in TB/HIV Co-infected Ghanaian Patients: UGT2B7*1C is Associated with Faster Zidovudine Clearance and Glucuronidation

There are limited data on the pharmacokinetics of generic nucleoside reverse transcriptase inhibitors (NRTIs) in native African populations, where they are commonly used. We characterized the pharmacokinetics of lamivudine (n=27), zidovudine (n=16) and stavudine (n=11) in HIV/TB co-infected Ghanaian...

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Détails bibliographiques
Auteurs principaux: Kwara, Awewura, Lartey, Margaret, Boamah, Isaac, Rezk, Naser L., Oliver-Commey, Joseph, Kenu, Ernest, Kashuba, Angela D.M., Court, Michael H.
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749505/
https://ncbi.nlm.nih.gov/pubmed/19628728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270009338482
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