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Eplerenone inhibits the intracrine and extracellular actions of angiotensin II on the inward calcium current in the failing heart. On the presence of an intracrine renin angiotensin aldosterone system

The influence of chronic administration of eplerenone on the intracrine as well as on the extracellular action of angiotensin II (Ang II) on L-type inward calcium current was investigated in the failing heart of cardiomyopathic hamsters (TO-2).For this, eplerenone (200 mg/kg/day) was administered or...

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Detalles Bibliográficos
Main Authors: De Mello, Walmor C., Gerena, Yamil
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749237/
https://ncbi.nlm.nih.gov/pubmed/18585409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.regpep.2008.06.003
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