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Prolonged exposure of cardiac cells to renin plus angiotensinogen reduces intracellular renin in the failing heart. On the role of angiotensin II–AT1 complex internalization

To investigate the influence of prolonged exposure of cardiac cells to renin plus angiotensinogen (Ao) on intracellular renin levels, myocytes were isolated from the ventricle of cardiomyopathic hamsters(TO-2) and incubated in Krebs solution contaning renin(128 pmol Ang ml/min) plus Ao (110 pmol Ang...

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Autors principals: De Mello, Walmor C., Gerena, Yamil
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769704/
https://ncbi.nlm.nih.gov/pubmed/19303904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.regpep.2009.03.005
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