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Metabolic reprogramming of periwinkle plant culture

We transformed an alkaloid biosynthetic gene with reengineered substrate specificity into Catharanthus roseus. The resulting transgenic plant cell culture produced a variety of unnatural alkaloid compounds when cocultured with simple, achiral, commercially available precursors that the reengineered...

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Autors principals: Runguphan, Weerawat, O’Connor, Sarah E
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749225/
https://ncbi.nlm.nih.gov/pubmed/19151732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.141
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