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Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: Functional role of a nuclear noncoding RNA

In many cells, mRNAs containing inverted repeats (Alu repeats in humans) in their 3′-untranslated regions (3′-UTRs) are inefficiently exported to the cytoplasm. Nuclear retention correlates with adenosine-to-inosine editing and is in paraspeckle-associated complexes containing the proteins p54(nrb),...

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Main Authors: Chen, Ling-Ling, Carmichael, Gordon G.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749223/
https://ncbi.nlm.nih.gov/pubmed/19716791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.027
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