Adeno-associated virus-mediated human C-reactive protein gene delivery causes endothelial dysfunction and hypertension in rats

BACKGROUND: Prospective studies have shown that C-reactive protein (CRP) is a predictor of hypertension. However, due to confounding variables a causal linkage between CRP and hypertension has not been clearly shown. We investigated whether high circulating human CRP concentrations can induce hypert...

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Hauptverfasser: Guan, Hongjing, Wang, Peihua, Hui, Rutai, Edin, Matthew L., Zeldin, Darryl C., Wang, Dao Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749215/
https://ncbi.nlm.nih.gov/pubmed/19056836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2008.115857
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