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pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling

Nod1 and Nod2 are members of the Nod-like receptor family that detect intracellular bacterial peptidoglycan-derived muramyl peptides. The biological effects of muramyl peptides have been described for over three decades, but the mechanism underlying their internalization to the cytosol remains uncle...

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Detalhes bibliográficos
Main Authors: Lee, Jooeun, Tattoli, Ivan, Wojtal, Kacper A., Vavricka, Stephan R., Philpott, Dana J., Girardin, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749154/
https://ncbi.nlm.nih.gov/pubmed/19570976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033670
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