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The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole
Bacterial invasion results in the rapid induction of an acute state of cytosolic amino acid (AA) starvation, provoked by host membrane damage. Bacteria-induced AA starvation, in turn, down-regulates mTOR signaling while triggering autophagy and the integrated stress response pathway dependent on GCN...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522883/ https://ncbi.nlm.nih.gov/pubmed/23259056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20122840 |
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