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β1 Integrin Deficiency Results in Multiple Abnormalities of the Knee Joint

The lack of β1 integrins on chondrocytes leads to severe chondrodysplasia associated with high mortality rate around birth. To assess the impact of β1 integrin-mediated cell-matrix interactions on the function of adult knee joints, we conditionally deleted the β1 integrin gene in early limb mesenchy...

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Detalhes bibliográficos
Main Authors: Raducanu, Aurelia, Hunziker, Ernst B., Drosse, Inga, Aszódi, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749151/
https://ncbi.nlm.nih.gov/pubmed/19586917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.039347
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