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Novel Roles of GATA1 in Regulation of Angiogenic Factor AGGF1 and Endothelial Cell Function

AGGF1 is an angiogenic factor, and its deregulation is associated with a vascular malformation consistent with Klippel-Trenaunay syndrome (KTS). This study defines the molecular mechanism for transcriptional regulation of AGGF1 expression. Transcription of AGGF1 starts at two nearby sites, −367 and...

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Detalhes bibliográficos
Main Authors: Fan, Chun, Ouyang, Ping, Timur, Ayse A., He, Ping, You, Sun-Ah, Hu, Ying, Ke, Tie, Driscoll, David J., Chen, Qiuyun, Wang, Qing Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749107/
https://ncbi.nlm.nih.gov/pubmed/19556247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.036079
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