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Biophysical Properties of Apolipoprotein E4 Variants: Implications in Molecular Mechanisms of Correction of Hypertriglyceridemia
In humans and animal models, high plasma concentrations of apolipoprotein (apo) E are associated with hypertriglyceridemia. It has been shown that overexpression of human wild-type (WT) apoE4 in apoE-deficient mice induces hypertriglyceridemia. In contrast, overexpression of an apoE4 variant, apoE4-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748909/ https://ncbi.nlm.nih.gov/pubmed/18959431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8015857 |
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