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Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long- but not short-access rats

Dysregulation of the stress-related corticotropin-releasing factor (CRF) system has been implicated in the development of drug dependence. The present study examined the effects of administering CRF type 1 (CRF(1)) receptor antagonists on heroin self-administration in animals allowed short (1 hour)...

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Autori principali: Greenwell, Thomas N., Funk, Cindy K., Cottone, Pietro, Richardson, Heather N., Chen, Scott A., Rice, Kenner C., Zorrilla, Eric P., Koob, George F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748834/
https://ncbi.nlm.nih.gov/pubmed/19291009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2008.00142.x
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