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Heat shock protein inhibitors increase the efficacy of measles virotherapy

Oncolytic measles virus strains have activity against multiple tumor types and are currently in phase I clinical testing. Induction of the heat shock protein 70 (HSP70) constitutes one of the earliest changes in cellular gene expression following infection with RNA viruses including measles virus, a...

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Bibliographic Details
Main Authors: Liu, C, Erlichman, C, McDonald, CJ, Ingle, JN, Zollman, P, Iankov, I, Russell, SJ, Galanis, E
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748733/
https://ncbi.nlm.nih.gov/pubmed/18356818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2008.30
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