Dexamethasone, Cerebrospinal Fluid Matrix Metalloproteinase Concentrations and Clinical Outcomes in Tuberculous Meningitis

BACKGROUND: Adjunctive dexamethasone reduces mortality from tuberculous meningitis, but how it produces this effect is not known. Matrix metalloproteinases (MMPs) are important in the immunopathology of many inflammatory CNS diseases thus we hypothesized that that their secretion is important in TBM...

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Autori principali: Green, Justin A., Tran, Chau T. H., Farrar, Jeremy J., Nguyen, Mai T. H., Nguyen, Phu H., Dinh, Sinh X., Ho, Nghia D. T., Ly, Chuong V., Tran, Hien T., Friedland, Jon S., Thwaites, Guy E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748711/
https://ncbi.nlm.nih.gov/pubmed/19789647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007277
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