Dexamethasone, Cerebrospinal Fluid Matrix Metalloproteinase Concentrations and Clinical Outcomes in Tuberculous Meningitis

BACKGROUND: Adjunctive dexamethasone reduces mortality from tuberculous meningitis, but how it produces this effect is not known. Matrix metalloproteinases (MMPs) are important in the immunopathology of many inflammatory CNS diseases thus we hypothesized that that their secretion is important in TBM...

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Autores principales: Green, Justin A., Tran, Chau T. H., Farrar, Jeremy J., Nguyen, Mai T. H., Nguyen, Phu H., Dinh, Sinh X., Ho, Nghia D. T., Ly, Chuong V., Tran, Hien T., Friedland, Jon S., Thwaites, Guy E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748711/
https://ncbi.nlm.nih.gov/pubmed/19789647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007277
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