Determination of Corynebacterium diphtheriae toxigenicity by a colorimetric tissue culture assay.

Chinese hamster ovary (CHO) cell cultures in microtiter wells are sensitive to growth inhibition and killing by picogram quantities of diphtheria toxin. In the absence of biologically active toxin, the CHO cell culture produces sufficient acidic metabolites to change the phenol red pH indicator from...

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Pubblicato in:	J Clin Microbiol
Autori principali:	Murphy, J R, Bacha, P, Teng, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1978
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC274864/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/415068/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.7.1.91-96.1978
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